Story
Quarantine
Destroy a powerful Vex Mind to breach the quarantine around the singularity and seize the final strangelet capsule.
Overview
Quarantine is mission 12 of the Destiny 2: The Edge of Fate campaign, set on Kepler (Oort Cloud) for 1-3 players. Destroy a powerful Vex Mind to breach the quarantine around the singularity and seize the final strangelet capsule. It is unlocked at step 3 of the The Gorge Strangelet quest (offered by Calculus) and has Normal and Legendary variants.
Walkthrough
- Fight through the Assimilated Easement, taking on Vex (Harpies, Goblins, Hobgoblins, Minotaurs, Cyclops) and House Exile Fallen.
- Use Matterspark to destroy marked objects and Mattermorph to alter terrain; disable the disruptors along the way.
- Destroy the two lenses in the trapped arena and defeat the Fallen Brig The Interred.
- Final boss: the Vex Mind Pagida Divided, the Choral Cage (with Unknown Cipher). Cycle through killing Vex combatants, destroying Vex Cubes and using Matterspark until it becomes vulnerable, then damage it.
Rewards
A chest with Enhancement Cores, Glimmer, Phaseglass Refraction and seasonal Legendary gear; the strangelet capsule; unlocks the Landing Zone in the Assimilated Easement and advances the campaign.
Rewards / drops
Location: Kepler
Required for
- Criticality
- Fabled Mission: Quarantine
- Forensic Horology
- Mythic Mission: Quarantine
- Skylines
- Skylines (activity)
- The Paper Crane
- The Paper Crane (activity)
- Transfer of Power
- Transfer of Power (activity)
Community guides & sources
destinypedia.com
QuarantineDestinypedia · destinypedia.com
progametalk.com
Destiny 2 Quarantine Mission Walkthrough (The Edge of Fate)ProGameTalk · progametalk.com
Category: Activities · Last edited 2026-10-01 23:35:22 UTC